August 2008

Detecting Early Ovarian Cancer

8.22.2008 Jen Smith
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Women should know – and watch for – these symptoms of ovarian cancer

Ovarian cancer has long been considered a “silent killer.” However, recent research has shown that certain symptoms are much
more likely to occur in women with ovarian cancer than in women in the general population.

Based on conclusive research, the Gynecologic Cancer Foundation and the Society of Gynecologic Oncologists have agreed on
a set of symptoms that can be signs of early ovarian cancer.

Because they often mimic common digestive and gastrointestinal disorders, the symptoms of ovarian cancer can be subtle and hard to assess. The symptoms include:

Ovarian Cancer Odds Lowered with High-Fiber, Low-Fat Diet

8.22.2008 Jen Smith
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Here’s another reason to eat right: It could lower your risk of ovarian cancer

Older women who stick to a low-fat, high-fiber diet could cut their odds for ovarian cancer, according to a report in the
Journal of the National Cancer Institute.
In fact, postmenopausal women who stayed on the regimen for more than
eight years reduced their risk for the disease by 40 percent,
researchers say. And those who saw the greatest benefit from the
low-fat diet were women who had originally eaten a relatively high-fat
diet, the researchers add.

On average, the women in the study had managed to add one serving of fruits or vegetables to their daily diet by the end of
the six-year follow-up. They had also reduced their daily fat consumption by about 8 percent.

The findings reinforce the importance of healthy diet and lifestyle, says Jefferson gynecologic oncologist Norman G. Rosenblum, MD, PhD.

“We know there’s a link between obesity and endometrial cancer and other forms of cancer, and so it’s not surprising to learn that there’s a connection between diet and ovarian cancer,” Dr. Rosenblum notes.

Besides helping curb cancer, Dr. Rosenblum notes that a low-fat, high-fiber diet would also be beneficial in reducing the
risk of other chronic diseases – such as heart disease.

Questions and Answers: Hormone Replacement Therapy

8.22.2008 Jen Smith
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Get answers to common questions about Hormone Replacement Therapy (HRT)

 
   
There’s no shortage of news reports about hormone replacement therapy (HRT) and its potential benefits and risks. We asked Jefferson
  obstetrician/gynecologist Abigail Wolf, MD, to cut through the confusion with a high-level overview.

    Abigail Wolf, MD

 

 
     

    Abigail Wolf, MD

 

Keep In Touch: In lay language, what is hormone replacement therapy (HRT), and how is
it typically administered to
patients?

Abigail Wolf, MD: Hormone replacement therapy is a complicated subject. Essentially, it’s administration of one or both of the hormones that
decrease in women during and after menopause. Those hormones are estrogen and progesterone.

An Interactive Education

8.22.2008 Jen Smith
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Online tools provide overviews of conditions, tests and treatments

Looking for information about orthopedic medicine? Chances are, you’ll find what you need in our library of animations.

The library covers more than 40 orthopedic topics – from common conditions and diagnostic tests to surgical treatments, including:

  • Arthritis and other rheumatic diseases
  • Osteoarthritis
  • Osteoporosis
  • Sports-related injuries
  • Low back pain
  • And more

You’ll find these multimedia presentations – including overviews about hip replacement, knee replacement, low back pain and vertebral fusion – in the Department of Orthopedic Surgery’s Health Information Library .

For an appointment, call 1-800-JEFF-NOW

To make an appointment with a Jefferson physician, call 1-800-JEFF-NOW. We’ll help you choose the doctor that’s right for you, based on types of medical insurance accepted, location, and any other factors that are important to you.

Keeping Hips Healthy

8.22.2008 Jen Smith
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Although most hip problems stem from genetic factors, there are some steps you can take to preserve your joints

A Lifetime Hip Replacement?

8.22.2008 Jen Smith
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Joint implants last longer than you may think – and research is helping further enhance their durability

Peter F. Sharkey, MD, is a joint specialist with the Rothman Institute at Thomas Jefferson University Hospital and professor of Orthopedic Surgery at Thomas Jefferson University. As such, he has extensive experience in treating patients with hip problems. And he’s nothing short of passionate about the life-changing results patients can experience through hip replacement.
 
  Keep In Touch
spoke with Dr. Sharkey to get his perspective on the benefits of this procedure – and the advantages of choosing a surgeon from the Rothman Institute at Jefferson. Dr. Sharkey Peter F. Sharkey, MD


Keep In Touch: We’ve talked about two other types of procedures for hip resurfacing and hip preservation. Is traditional hip replacement still an option for many patients?

Hip Resurfacing Patients: From Excruciating Pain to Full Activity

8.22.2008 Jen Smith
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In this innovative procedure, the surgeon shapes an arthritic or damaged joint and then covers both sides with metal prosthetic implants
                              

Hip resurfacing surgery was introduced in the United States in 2006. Today, the results are extremely positive.

William
Hozack, MD, an orthopedic surgeon with the Rothman Institute at Thomas
Jefferson University Hospital and professor of Orthopedic Surgery at
Thomas Jefferson University, has performed hip resurfacing on some 50
patients. Many of them are raving about the results – and are relieved
to be free of pain.

“No
pain, no limp, no complaints,” says Anthony DiSalvo, 49, of Deptford,
NJ, who previously considered traveling to Europe where the surgery had
been approved. His hip was resurfaced in May 2007 at Thomas Jefferson
University Hospital.

Virtual Tour: HeartCARE at Jefferson

8.19.2008 Jen Smith
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Get a behind-the-scenes look at HeartCARE at Jefferson

The Heart Care center at Jefferson offers a comprehensive range of treatment options unequaled in the Delaware Valley. Learn more through our online virtual tours about Heart Care at Jefferson – as well as Jefferson’s Advanced Heart Failure and Cardiac Transplant Center.

These tours deliver a multimedia preview of our capabilities and what you can expect as a patient at Thomas Jefferson University Hospital.

Heart Disease by the Numbers

8.19.2008 Jen Smith
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Every 34 seconds, an American dies of cardiovascular disease

Each
year, heart disease tops the list of the country’s most serious health
problems. In fact, statistics show that cardiovascular disease is
America’s leading health problem – and the leading cause of death.

These statistics clearly illustrate the scope and severity of heart disease in the United States:

Winter Months Bring Elevated Blood Pressure, Experts Say

8.19.2008 Jen Smith
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Here’s what you need to know about seasonal and other variations in blood pressure
                   

It
turns out blood pressure has a chill factor: Hypertension is harder to
control in colder weather, according to a study that used the Veterans
Administration’s (VA) storehouse of 1.8 billion vital statistics
records.

The
five-year study covered almost 1.2 million Veterans Administration
patients cared for at 15 VA hospitals located at different latitudes:
Anchorage; Baltimore; Boston; Chicago; Fargo, ND; Honolulu; Houston;
West Los Angeles; Miami; Minneapolis; New York City; Philadelphia; San
Juan, Puerto Rico; Portland, Oregon; and Washington, DC.

The average age of participants was 66. Fifty-one percent were Caucasian, 21 percent were Hispanic, and 27 percent were African
American. Less than 4 percent were female.

Within the sample, almost 444,000 veterans had high blood pressure (based on readings of more than 140/90 on three separate days).

Breast and Ovarian Cancer Genetics: What’s the Connection?

8.12.2008 Jen Smith
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Come learn and ask questions about breast and ovarian cancer genetics and genetic testing.

Date: Wednesday, September 24, 2008 Time: 6:30pm - 7:30pm Location: Methodist Hospital
2301 South Broad Street
Morgan Conference Room
Lower level of hospital Speaker: Sue Miller-Samuel, RN, MSN, APNG
Jefferson Breast Care Center
Thomas Jefferson University Hospital
Free to the community and light refreshments will be provided.

To register, call 1-800-JeffNOW

The Power of Mind-Body Therapies

8.12.2008 Jen Smith
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Jefferson expert notes that complementary and alternative medicine can benefit cancer survivors and enhance the doctor-patient relationship

Traditionally, many physicians have had some difficulties advocating the use of complementary and alternative medicine (CAM) in treating cancer for a variety of reasons – including a lack of scientific evidence. But a specialist in the field at Thomas Jefferson University Hospital contends that doctors could be missing out on a potential opportunity.

As the number of cancer survivors continues to climb, physicians need to be more open to discussing the potential use of mind-body therapies, such as various stress-reduction techniques, which are increasingly popular and the use of which in some cases is supported by scientific evidence, says Daniel Monti, MD, director of the Jefferson-Myrna Brind Center of Integrative Medicine at Thomas Jefferson University Hospital.

“Many have been found to help with quality of life issues – from stress to pain to coping with a cancer diagnosis,” Dr. Monti notes.

Halting the Spread of Cancer?

8.12.2008 Jen Smith
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Jefferson researchers begin to pinpoint new therapeutic targets to block spread of breast cancer

Scientists at the Kimmel Cancer Center at Jefferson have made a key discovery about the mechanism of breast cancer metastasis – the process by which cancer spreads. Focusing on a gene dubbed “dachshund,” or DACH1, they are beginning to pinpoint new therapeutic targets to halt the spread of cancer.

Reporting their findings in the Proceedings of the National Academy of Sciences, researchers led by Richard Pestell, MD, PhD, director of the Kimmel Cancer Center at Jefferson and professor and chair of Cancer Biology at Jefferson Medical College, showed that breast cancer cells secrete a common inflammatory protein, IL-8. When the scientists blocked the protein in mice with an antibody, they found that it completely halted the spread of breast cancer to the lungs.

In addition, the team found that the DACH1 gene normally blocks the production of IL-8.

Research News: Prostate Cancer

8.12.2008 Jen Smith
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Recent Kimmel Center at Jefferson studies shed light on how prostate cancer spreads – and how physicians can reduce the number of unnecessary biopsies

If you or someone you care about has been diagnosed with prostate cancer, turn to the Kimmel Cancer Center at Jefferson’s Multidisciplinary Genitourinary Center. Founded in 1996, the Multidisciplinary Genitourinary Center gives you access to not only Jefferson urologists but also experts in radiation oncology, medical oncology and integrative medicine. The center’s progressive approach enables patients to benefit from these multiple areas of expertise in a single visit.

Just as important, patients of the Center benefit from the ongoing research initiatives at Kimmel Cancer Center at Jefferson. Two recent examples: studies into how prostate cancer spreads and how physicians can use a special ultrasound technique to reduce unnecessary prostate biopsies.

Study #1: Blocking the spread of prostate cancer

Jefferson Journaling: A Program for Women Facing Cancer

8.12.2008 Jen Smith
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Come learn tools and techniques that will either get you started or enhance your journaling experience.
                         
Date:

Monday August 25, 2008
                         
Time:

12noon -1P
                         
Location

Jefferson's Kimmel Cancer   Center- Bodine Building
111 South 11th Street (corner of Sansom and 11th Streets)
Simon Kramer Conference Room
Ground Floor Room G312

To register, call 1-800-JeffNOW

Heart Risk Linked to Pot Belly

8.12.2008 Jen Smith
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Even so, focusing on the belly alone may not be the best way to address the risk

A new study published in the Journal of the American College of Cardiology
underscores that “pot” bellies may be a big indicator of future heart
disease. The researchers reported seeing a strong association between
the pot-belly or apple shape and atherosclerosis, or hardening of the
arteries, among a relatively young group of people.
Heart Risk Linked to Pot BellyThe
researchers focused on data collected between 2000 and 2002 on more
than 2,700 men and women between the ages of 30 and 65 who were
participating in the larger, multi-ethnic Dallas Heart Study. They also
took blood and urine samples from all the participants following
completion of a general health survey.

A
subsequent clinical exam calculated both weight and body mass index
(BMI) – a common obesity measurement based on weight-to-height ratios –
as well as waist and hip circumference.

All
the men and women then underwent non-invasive imaging tests, including
magnetic resonance imaging (MRI), to assess atherosclerosis and/or
electron beam computed tomography (EBCT) that specifically looked at
arterial calcium deposits in the heart. (EBCT is also called ultrafast
CT.) Such calcium deposits collect years before the onset of chest
pains or a heart attack.

Innovative Procedures Help Preserve Hips

8.12.2008 Jen Smith
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Surgeries help treat hip dysplasia and impingement in younger individuals
                              

For young patients suffering from hip dysplasia or impingement, replacement and resurfacing used to be the only treatment
options. That’s no longer the case.
                              

Today,
Javad Parvizi, MD, joint specialist at the Rothman Institute at Thomas
Jefferson University Hospital, performs two innovative procedures that
treat pain and loss of mobility by preserving a patient’s native hip
joint – rather than replacing or resurfacing it.

And he is the only orthopaedic surgeon in the Philadelphia region and one of only about a dozen in the United States to do so.
                              
                              

Keep In Touch With Thomas Jefferson University Hospital

8.12.2008 Jen Smith
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Your Health Delivered Your Way

Keep in Touch With Jefferson is a way to allow you to receive health content and important Jefferson updates the way you want to receive them - whether it is via email or RSS Feed, on your computer or on your mobile device. This is not a blog. On this site you can:

Understanding Pancreatic Cancer

8.12.2008 Jen Smith
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Three studies shed light on the science behind the development and behavior of this disease

Claiming
some 34,000 lives a year, pancreatic cancer is the fourth-leading cause
of cancer death in the United States. The disease frequently is
detected after it has spread, and only 4 percent of individuals with
pancreatic cancer live for five years after diagnosis.

The Jefferson Center for Pancreatic, Biliary and Related Cancers
is leading the fight against pancreatic cancer. In addition to
performing the highest volume of pancreatic surgeries of any center in
the tri-state area, this team also actively explores the basic science
behind the development and behavior of the disease.

In
recent months, the team has announced the findings of three significant
studies led by Hwyda Arafat, MD, PhD, associate professor of Surgery at
Jefferson Medical College of Thomas Jefferson University. The work of
Dr. Arafat and her colleagues reinforces the advantages of seeking treatment at Jefferson.